p32 Inhibitor M36
CAS No. 802555-85-7
p32 Inhibitor M36( —— )
Catalog No. M25043 CAS No. 802555-85-7
p32 inhibitor M36 (M36) is a p32 mitochondrial protein inhibitor, which binds directly to p32 and inhibits p32 association with LyP-1.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 50MG | 606 | In Stock |
|
| 100MG | 897 | In Stock |
|
| 200MG | Get Quote | In Stock |
|
| 500MG | Get Quote | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
-
Product Namep32 Inhibitor M36
-
NoteResearch use only, not for human use.
-
Brief Descriptionp32 inhibitor M36 (M36) is a p32 mitochondrial protein inhibitor, which binds directly to p32 and inhibits p32 association with LyP-1.
-
Descriptionp32 Inhibitor M36 inhibits SF188 glioma cells proliferation (IC50 of 77.9 μM in complete media) and is much more potent under low glucose conditions with an IC50 of 7.3 μM.p32 Inhibitor M36 is selective for p32 overexpressing cells.p32 Inhibitor M36 is also a potent inhibitor of patient-derived neurospheres with an IC50 of 2.8 μM.
-
In Vitrop32 Inhibitor M36 inhibits SF188 glioma cells proliferation (IC50 of 77.9 μM in complete media) and is much more potent under low glucose conditions with an IC50 of 7.3 μM. p32 Inhibitor M36 is selective for p32 overexpressing cells.p32 Inhibitor M36 is also a potent inhibitor of patient-derived neurospheres with an IC50 of 2.8 μM.
-
In Vivo——
-
Synonyms——
-
PathwayAngiogenesis
-
TargetPKC
-
RecptorM36
-
Research Area——
-
Indication——
Chemical Information
-
CAS Number802555-85-7
-
Formula Weight448.52
-
Molecular FormulaC23H28N8O2
-
Purity>98% (HPLC)
-
SolubilityIn Vitro:?DMSO : 5 mg/mL (11.15 mM)
-
SMILES——
-
Chemical Name——
Shipping & Storage Information
-
Storage(-20℃)
-
ShippingWith Ice Pack
-
Stability≥ 2 years
Reference
1. Yenugonda V,et al. A novel small molecule inhibitor of p32 mitochondrial protein overexpressed in glioma. J Transl Med. 2017 Oct 18;15(1):210.
molnova catalog
related products
-
HG-9-91-01
HG-9-91-01 is a potent and highly selective salt-inducible kinase (SIKs) inhibitor with?IC50s of 0.92 nM, 6.6 nM and 9.6 nM for?SIK1, ?SIK2?and?SIK3respectively.
-
ICA-1
ICA-1 is a potent, specific inhibitor of Protein Kinase C-iota (PKC-ι) with IC50 of 0.1 uM.
-
TV 3279
TV 3279 is a novel ChE-MAI inhibitor , and the neuroprotective properties depend on their ability to induce the anti-apoptotic proteins PKC, Bcl-2, Bcl-x, and SOD, and to block the nuclear translocation of the pro-apoptotic enzyme glyceraldehyde phosphate dehydrogenase in PC-12 and neuroblastoma cells.
Cart
sales@molnova.com